The Orphan Drug designation is based on data from the dose escalation phase of the open-label phase 1/2 study.
Researchers identified nicotinamide (NAM) and pyridoxine (PN) as safe, synergistic nutrients that restore muscle stem cell ...
【导读】Wnt/β-catenin/转录因子(TCF)转录活性在结直肠癌(CRC)的发生发展中起着不可或缺的作用。然而,迄今为止,靶向该 ...
[miR-497 inhibits the growth and metastasis of SGC-7901 human gastric cancer anoikis resistant cells via blocking Wnt/β-catenin signaling pathway]. [Formononetin improves cognitive behavior in ...
FOG-001, the company’s first-in-class TCF-blocking β-catenin inhibitor and lead clinical program, is being evaluated in a Phase 1/2 study for patients with colorectal cancer and other solid ...