The processing of the 3' end adds a poly-A tail to the RNA molecule. First, the 3' end of the transcript is cleaved to free a 3' hydroxyl. Then an enzyme called poly-A polymerase adds a chain of ...
Get Instant Summarized Text (Gist) A mechanism regulating mRNA poly(A) tail length in early embryos has been identified, involving the protein MARTRE1, which inhibits the CCR4-NOT complex. MARTRE1 ...
translation and degradation that result from the presence of a stem–loop rather than a poly(A) tail at the 3′ end of the mRNA. In addition, we do not yet understand the precise signalling ...
Communications》期刊在线发表了题为"MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA"的研究工作 ...