Many eukaryotic genes have a conserved promoter sequence called the TATA box, located 25 to 35 base pairs upstream of the transcription start site. Transcription factors bind to the TATA box and ...

Crish and Robert L. Eckert, which discloses the isolation and sequencing of the promoter sequence of human involucrin (hINV), a protein that interacts with keratin within epithelial cells.

with the first referring to the generally recognized E1 and E2 boxes and the second number representing all CANNTG sequences up to position –400 or the 5' limit of available promoter sequence.