A human cell culture model of the lung’s most important immune cells, alveolar macrophages, helped make a key finding that is ...

Four leading cancer research organizations in the United States and Canada announce the opening of patient enrollment to ...

Patients with Acute Myeloid Leukemia (AML ... company of Clinical Trials Arena. Cell therapies are used as supportive products after hematopoietic stem cell transplants (HSCT) that aim to either ...

AML originates from a rare population of cells, termed leukemic stem cells (LSCs) or leukemia-initiating cells, which are capable of self-renewal, proliferation and differentiation into malignant ...

"As scientists, we want to make discoveries ... These AML cells are currently being evaluated in more complex lung-on-chip models and the specialized ingredients tested with stem cells to generate ...

A study utilizing alveolar macrophage-like (AML) cells revealed that tumor necrosis factor (TNF) is critical for fighting ...

Fred Hutch Madeline Dabney Adams Endowed Chair in AML Research Fred Hutch Dr. Effie Wang Petersdorf is an oncologist who studies how genetic factors influence the success of stem cell transplants. She ...

For example, if they shared a similar origin, such as mutations in cell lineages (a set of cells that come from the same stem cell) from embryonic ... they developed therapy-related acute myeloid ...

Targeting self-renewal, the process by which stem cells divide and generate progeny ... to be selectively cytotoxic to primary LSCs from AML and other leukemias within 2 h after drug exposure ...