Some drugs can activate AMPK, most prominently metformin, which is approved for diabetes and being trialed in dementia. Less well-known is aldometanib, developed by Lin’s team, which blocks aldolase, ...
AMPK signaling promotes an increase in cell stiffness that drives entotic ingestion ... environment in particular has been shown to promote the growth of Ras-mutant pancreatic cancers, and may be an ...