Abiraterone acetate (CB7630), a pregnenolone analog, is an orally administered small molecule that irreversibly inhibits a rate-limiting enzyme in androgen biosysnthesis, CYP17, and blocks the ...
Giles Turner, from Sussex, is paying for abiraterone privately at a cost of £250 per month Thousands of patients in England and Northern Ireland are missing out on a life-extending prostate ...
Future Oncol. 2010;6(5):665-679. Three Phase I studies by O'Donnell and colleagues have reported the pharmacodynamic activity of abiraterone acetate, which was originally developed as an oral ...