Chronic neuroinflammation ... and highlights the contribution of three types of glia cells: microglia, astrocytes and oligodendrocytes, to disease. Microglia, often referred to as the nervous ...

and these proliferative astrocytes were found in close proximity to activated microglia and neurons, strategically positioned to allow such cross-talk. In summary, neuroinflammation and ongoing ...

The authors show that neuroprotective and neurotoxic astrocytes represent transitional cellular substates present during neuroinflammation and that targeting mTOR in astrocytes reduces ...