2008;3(6):691-697. Elimination of sitagliptin occurs primarily via renal excretion (79%) and involves active tubular secretion. Sitagliptin is a substrate for human organic anion transporter-3 ...

50]; increase in creatinine production by stimulation of muscle turnover [50] and inhibition of active tubular creatinine secretion [48] † Usual effects seen in patients with diabetes.