Management. Salvage chemotherapy regimens including bortezomib plus steroid, alkylators plus steroid, bortezomib plus anthracycline and radiotherapy, and combined bortezomib, cyclophosphamide ...

Treatments for MM, which include alkylators, steroids, immunomodulatory drugs, proteasome inhibitors, and anti-CD38 antibodies, used individually or in combination, have helped increase the five ...

Bendamustine is a unique alkylating agent with structural and mechanistic qualities that seem to distinguish it from conventional alkylators. It has been in use for several decades in Germany to ...

The mechlorethamine (nitrogen mustard) group is shared with the alkylators cyclophosphamide and chlorambucil; bendamustine is chemically related to those molecules. The benzimidazole ring ...