Interactions between β-catenin and LEF ... We also show that complementary charged and hydrophobic amino acids are required for formation of the bipartite β-catenin–LEF-1 transcription factor.

Other amino acids avoid water and are called hydrophobic, such as isoleucine ... The sequence and interactions between the side chains of these different amino acids allow each protein to fold ...

The sequence of amino acids in a protein, known as its primary structure, determines its unique three-dimensional shape and function. Proteins can further fold and assemble into complex structures, ...

The Structural and Functional Diversity of Peptides Studies suggest that peptides may exhibit remarkable diversity in structure and function, which arises from variations in amino acid composition, ...