Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell ...

“We found that mitochondria provide a kind of decision-making aid: they regulate whether a cell undergoes clean, silent apoptosis or releases pro-inflammatory messenger substances,” explains Pro ...

and thereby steer the direction of cell migration. (6) Mitochondria-associated membranes (MAMs), the contact sites between mitochondria and ER, are a central hub for Ca2+ signaling, apoptosis ...