The Flow Cytometry and Cell Separation Facility provides advanced cell sorting and cell analysis techniques including immunofluorescence detection of 18 colors, cell-cycle distribution, apoptosis ...

In multicellular organisms, the total number of cells is a balance between the cell-generating effects of mitosis and cell death that is induced through apoptosis. A disruption of this delicate ...

Cell condensation during early apoptosis is seen as a decrease in forward light scatter only. As apoptosis proceeds, both forward and 90 o side scatter diminish. In necrotic death, cells swell ...

The influence of doxorubicin on apoptosis was studied by flow cytometry analysis. A doxorubicin dose-dependent increase in apoptosis rate of FTC 238 and FTC 133 cells was demonstrated by annexin V ...

In normal cells, phosphatidylserine (PS) residues are found in the inner membrane of the cytoplasmic membrane. During apoptosis, the PS residues are translocated in the membrane and are externalised.

Apoptosis is a series of sequential events under genetic control resulting in cell death (Darzynkiewicz et al., 1998; Penninger and Kroemer, 1998). It is seen during fetal development (e.g. loss of ...