In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...
To investigate the molecular mechanisms underlying accelerated diabetic atherosclerosis, we developed a murine model for this. Accelerated formation of complex atherosclerotic lesions in diabetic ...
Moritz Lehners, Hannes Schmidt, Maria T K Zaldivia, Daniel Stehle, Michael Krämer, Andreas Peter, Julia Adler, Robert Lukowski, Susanne Feil, Robert Feil: Single-cell analysis identifies the ...
Atherosclerosis and related cardiovascular diseases represent one of the greatest threats to human health worldwide. Despite important progress in prevention and treatment, these conditions still ...
Atherosclerosis is a chronic ... This is the progressive stage of plaque formation, characterized by the migration of SMCs into the intima, attracted by signals from the foam cells.
Knowing that sphingolipids promote atherosclerotic plaque formation reveals another side ... SPT activity did decrease trans fat-induced atherosclerosis. According to Metallo, these findings ...
The formation of these plaques can narrow or ... Moreover, progression of carotid atherosclerosis provided further prognostic information and was independently associated with all-cause mortality.