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17 天
中国博后一作Cell论文:发现帮助癌细胞逃逸CAR-T细胞治疗的关键蛋白 ...
该研究首次发现, YTHDF2促进 B细胞恶性肿瘤的能量供应和抗原逃逸,仅其过表达就足以引起B细胞转化和肿瘤发生。更重要的是,研究团队还证实,一种名为 CCI-38的小分子能够靶向和抑制 YTHDF2,从而抑制侵袭性B细胞恶性肿瘤并提高 CAR-T ...
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