The molecular components of these systems are typically cellular machineries such as haemolysin 5, porin 6, myosin 7, kinesin 8, RNA polymerase 9 and ATP synthase 10. These machines can be set in ...
of ATP synthase. A connecting shaft causes the upper motor (F1) to rotate While synthesizing ATP. This two-motor-like molecule, which has great likeness to an actual macroscopic motor, can also be run ...
TMC207 inhibits the proton pump of mycobacterial ATP synthase, a critical enzyme in the synthesis of ATP for Mycobacterium tuberculosis. The maximum plasma concentration (C max) is reached after 5 ...