induces autophagy. However, it is now clear that there are also TOR-independent types of regulation. For example, beclin-1 and Atg4 might be regulated by the c-Jun N-terminal kinase (JNK ...

01 英国牛津大学拉德克利夫医院的研究团队在Cell杂志上发表了一篇论文，发现TEX264介导的核吞噬作用在维持基因组稳定性和细胞存活中发挥关键作用。

Organismal lifespan can be extended by genetic manipulation of cellular processes such as histone acetylation, the insulin/IGF-1 (insulin-like ... been associated with autophagy (a cytoprotective ...

A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy.

Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...

A research team has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target. In their study, the researchers revealed that an ...

Conversely, inhibition of spermidine synthesis, using appropriate inhibitors, counteracts the benefits of autophagy on ...

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“Fashion continues to turn against hatches so the 1 Series range has shrunk. But if a petrol auto suits you this is a fine car” It's one of the most satisfying compact hatches around. Much ...

Devara Part 1 box office collection day 1: The film did well in India on Friday. It stars Jr NTR, Saif Ali Khan, and Janhvi Kapoor in lead roles. Devara Part 1 box office collection day 1 ...