来自中山大学生命科学学院的研究人员，与深圳华大基因合作，利用基因组DNA甲基化检测黄金方法Bisulfite Sequencing (BS-Seq)，对黄曲霉全基因组DNA甲基化进行了测序，首次证明黄曲霉是一种缺乏DNA甲基化的生物。 这是在世界上第一次使用黄金标准方法—Bisulfite ...

Pairing bisulfite conversion of the human genome with targeted enrichment and high-throughput sequencing allows a quantitative assessment of DNA methylation at base-pair resolution. A DNA molecule ...

Among the various approaches, bisulfite sequencing is the most widely adopted. The process involves treating a DNA sample with sodium bisulphate, which has the effect of making methylated cytosine ...

In recent years, microarray-based technologies have been gradually replaced by more robust, accurate and versatile next generation sequencing-based methods. This presentation will introduce ...

For more information, please visit the 10X website. Chromatin immunoprecipitation sequencing allows for genome-wide profiling of protein-DNA interactions and of histone PTMs. GARP offers ChIP-seq ...

Correlated regions of systemic inter-individual epigenetic variation (CoRSIV) target-capture bisulfite sequencing allows researchers to identify disease-associated epigenetic variation. Epigenetic ...

This bisulfite-free method of methylation detection ... in clinical research and epigenetics who often face challenges sequencing samples less than 10 ng that are below the input range of ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic ...

Discover how ctDNA methylation biomarkers enhance gastric cancer monitoring, providing a non-invasive method for prognosis ...