Selective depletion of B lymphocytes could represent a novel approach to the management of patients with newly diagnosed type 1 diabetes mellitus (T1DM), according to phase II data reported by the ...
More importantly, most patients treated with CD19 or B cell maturation antigen ... including tumor-infiltrated lymphocyte (TILs), CAR-T cells, and T cell receptor (TCR)-T cells, to overcome ...
Tumor-infiltrating lymphocytes (TILs ... and often restricted access to these therapies. Anti-CD19 CAR-T cells can expand rapidly in the recipient, causing significant increases in proinflammatory ...
It is a two-component therapy consisting of SYNCAR-001, an autologous CD19-targeting chimeric antigen receptor T (CAR-T) cell which expresses an engineered IL-2 receptor, and STK-009, an ...