During antigen recognition, CD4 or CD8 molecules act as co-receptors ... meaning they can recognize more than one peptide-MHC 1. Why is high-throughput multi-dimensional T cell profiling important?
CD4+ and CD8+ T cells accumulate in the skin of patients with psoriasis. These cells are also identified by markers of activation (e.g., increased IL-2 receptors and HLA-DR surface molecules) and ...