导 语快收藏！药是一把双刃剑，用对了可以救人，用错了可以害人，甚至致人于死亡。用药不当主要表现在：单次用药剂量过大，用药品种过多，造成重复用药；错误的联合用药；擅自用药或停药。注意！以下药物最好不要联合使用，后果很严重。这些药最好不要联合使用1、红霉素肠溶片+氨茶碱+复方甲氧那明胶囊=氨茶碱中毒红霉素可 ...

The best explored example of this phenomenon is the CYP2C19 polymorphism. In this table the most frequent alleles are presented that are important for the clinical practice [11,16]. Data on rare ...

Omeprazole, the prototype drug of PPIs, is metabolized primarily by CYP2C19 to 5-hydroxyomeprazole. 5-hydroxyomeprazole is then transformed into 5-hydroxyomeprazole sulfone by CYP3A4. Omeprazole ...