Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells ...

In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton ... especially for cancer. To tackle these questions, we use a multidisciplinary approach combining ...

cell division, endocytosis, and phagocytosis. The organization and dynamics of actin filaments must be precisely controlled during these processes, and consequently defects in regulation of the actin ...

Programmed or not, cell death is an essential process that cancer is adept at avoiding ... an accumulation of disulfide bonds in the actin cytoskeleton, and ultimately cell death.

When applied to breast cancer cell lines in vitro ... In addition, MicroQuin compounds act on the actin cytoskeleton to block the formation of F-actin in cancerous cells and inhibit their ...

We want to understand how these changes are co-ordinated by dynamic regulation of the actin cytoskeleton throughout ... maintain attachment with neighbouring cells to preserve tissue integrity and ...

For this, he uses a soft substrate and high-resolution live-cell fluorescence microscopy and develops novel force reconstruction technique, image modeling and machine learning technique to probe ...