The discovery of the mRNA cap offers one example of growing realization. “capping might be more complex than initially thought.” In the mid 1970s, biochemical analyses, such as those carried ...

The N-terminal ATP-dependent ligase domain belongs to the covalent nucleotidyltransferase enzyme superfamily that includes classic RNA/DNA ligases and mRNA capping enzymes. We’ve shown that: (i) each ...

The popularity of mRNA-based therapeutics has surged over the past few years. To ensure the safety of these treatments, scientists need to analyze the characteristics of the manufactured molecules, ...

(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...