There is evidence to indicate that full adrenergic blockade by carvedilol improves survival and cardiovascular outcome in patients with heart failure compared with metoprolol treatment ...

Patients were switched if they were stable on a minimum dose of 25 mg b.i.d. carvedilol or 100 mg metoprolol. The crossover was performed within 1 day during monitoring of blood pressure and heart ...

A number of comparative studies have been performed with metoprolol, a β 1-selective "second-generation" β blocker, and carvedilol, a nonselective and vasodilatative "third-generation" β blocker.

The classification of drugs have been around since 1964 after Sir James Black discovered how they can assist people with ...