The study of the cell cycle focuses on mechanisms that regulate the timing and frequency of DNA duplication and cell division. As a biological concept, the cell cycle is defined as the period ...

Cell cycle transitions in eukaryotes are driven by cyclin-dependent kinases (for example, Cdk1 and Cdk2), which are regulated by the availability of their cyclin partners (for example, CycA and ...

Harvest cells, want good single cell suspension Count cells Dispense aliquots of 1 million cells into labeled tubes Add 5 ml PBS and centrifuge for 5 min at 400 x g. Re-suspend cell pellet in 300 ul ...

When looking at cells with a microscope, the length of different stages of the cell cycle can be estimated using the formula: \(\text{Length of time in phase}=\) \(\frac{\text{observed number of ...

Before a cell can divide, it must grow and make copies of all the organelles such as mitochondria and ribosomes. The cell must also replicate the chromosomes in the nucleus, then it can divide by ...

Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and ...

Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell ...

Fadraciclib is under clinical development by Cyclacel Pharmaceuticals and currently in Phase II for Unspecified B-Cell Lymphomas.