CHK1 is important for the activation of S, G2 checkpoints in response to DNA damage and replicative stress and is involved in DNA repair. In addition, studies have shown that in tumour cells which are ...

This concept underscores an important feature: presence of ssDNA signals that "something is wrong" and this also holds true for other phases of the cell cycle ... kinase 1 (Chk1) (Figure 4 ...

Whereas much has been learned at a molecular level about the mechanisms that orchestrate progression through the different cell-cycle phases, little is known about how the cell-cycle machinery ...

When looking at cells with a microscope, the length of different stages of the cell cycle can be estimated using the formula: \(\text{Length of time in phase}=\) \(\frac{\text{observed number of ...