This concept underscores an important feature: presence of ssDNA signals that "something is wrong" and this also holds true for other phases of the cell cycle ... kinase 1 (Chk1) (Figure 4 ...
Whereas much has been learned at a molecular level about the mechanisms that orchestrate progression through the different cell-cycle phases, little is known about how the cell-cycle machinery ...
US-Canadian clinical-stage precision oncology company, Repare Therapeutics, has unveiled positive data from its Phase I gynecologic ... that treatment targets cell cycle regulation in tumours.