It is thought that these proteins play a role in preventing recombination during DNA replication when it is not needed. An alternate hypothesis proposes that homologous chromosomes reside in pairs ...

is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genetics 9, e1003945. Cole F, Baudat F, Grey C, *Keeney S, *de Massy B ...

What does monoallelic gene expression have to do with cats, twins, and genetic diseases? Therefore, research has demonstrated that there is a class of autosomal genes that show monoallelic expression.

so it does not have the opportunity to go through genetic recombination, or the "shuffling of genes that occurs in each generation which helps to eliminate damaging gene mutations," Darren Kent ...

It is one of the final phases of genetic recombination, which occurs in the pachytene stage of prophase I of meiosis during a process called synapsis. Synapsis begins before the synaptonemal complex ...

Because Y chromosomes contain completely different genes to Xs, they can’t recombine with them. Recombination is a process by ...

In Meiosis I homologous chromosomes separate, which requires pairing, synapsis, and recombination. In Meiosis II sister chromatids segregate from each other similarly to mitosis. Meiotic events must ...

Factors like genetic recombination, environmental influences, and even recessive traits passed down through generations play ...

Several projects in the lab focus on Spo11 (the protein that makes the DNA double-strand breaks (DSBs) that initiate recombination), the proteins that interact with Spo11, the interactions of these ...

The topics covered in the module include experimental approaches to address the function of specific genes, mechanisms of regulated gene expression, DNA repair and recombination pathways, chromosome ...