Systemic mastocytosis is a rare health condition in which too many mast cells (a type of immune system cell) build up in the body, causing allergic reactions and other health issues. This disorder ...

Citation: Advances in systemic mastocytosis: Early signs of efficacy for novel drug and new predictive tool to guide patient care (2024, December 9) retrieved 5 January 2025 from https ...

Mastocytosis is a rare disorder that develops when the immune system overproduces mast cells—a type of white blood cell that ...

DeAngelo, Shimony, and Volpe combed through data from three previous clinical trials of an earlier KIT D816V inhibitor, called avapritinib. These trials -; EXPLORER (NCT02561988), PATHFINDER ...

In September of 2000, the world's leading experts in MC met to discuss and present data at the "Year 2000 Working Conference on Mastocytosis," held in Vienna, Austria. Table 1 presents a uniform ...

Systemic mastocytosis (SM) is a rare disease driven by the KIT D816V mutation in about 95 percent of cases. Uncontrolled proliferation and activation of mast cells result in chronic, severe and ...

and gastrointestinal stromal tumors as well as aggressive systematic mastocytosis, hypereosinophilic syndrome, chronic eosinophilic leukemia, and dermatofibrosarcoma protuberans. FDA Approves ...

chronic myeloid leukemia, myelodysplastic syndromes, acute leukemia, eosinophilic disorders and systemic mastocytosis. He also serves as division resource for anemia, porphyria, hemochromatosis ...