Clonidine HCl 0.1mg ... β-blockers); avoid. Additive effects with antihypertensives; monitor. Hypotensive effects may be antagonized by tricyclic antidepressants; monitor. May need to adjust ...

Patients in the clonidine group withdrew due either to adverse effects, with 3 patients developing symptomatic orthostatic hypotension, or lack of efficacy, with 2 patients experiencing seizures ...