In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was inhibited only ... nonsteroidal anti-inflammatory drugs (NSAIDs).
All NSAIDs variably inhibit COX-1 and COX-2 and the mechanisms of inhibition fall into three broad categories, although there are exceptions. For example, nimesulide is a weak competitive ...
Most NSAIDs block both Cox-1 and Cox-2 enzymes. They include the over-the-counter drugs: Aspirin has some benefits that other NSAIDs do not. The biggest is that aspirin works against the formation ...
Generally speaking, there are two types: nonselective, which blocks both COX-1 and COX-2 enzymes, and selective, which primarily blocks COX-2 enzymes. 2 Nonselective, such as aspirin, ibuprofen ...