Patients aged 65 years and older who use acetaminophen demonstrate greater risks for serious complications, including ...

Both aspirin and ibuprofen inhibit COX-1 and COX-2, but acetaminophen appears to inhibit only COX-3. Very recently, additional anti-inflammatory agents have been introduced, ones that inhibit COX ...

This hypothermic effect of paracetamol was reduced in COX-1 but not in COX-2 gene-deleted mice. These results support the view that analgesia and hypothermia due to paracetamol are mediated by ...

Exactly how Tylenol — also called acetaminophen or paracetamol — relieves pain continues to evade scientists, but it's clear the drug interacts with one key set of enzymes.

Acetaminophen 1000mg ... but involves inhibition of cyclooxygenase (COX-1 and COX-2). Because ibuprofen is also an inhibitor of prostaglandin synthesis, its mode of action may be due to a decrease ...