Adverse GI events are less common with COX-2 inhibitors than with NSAIDs, but we still have to weigh overall harms and benefits before prescribing these agents. Many trials have indicated that ...

The idea seems plausible on its face. COX inhibitors seem to affect sexual behavior by blocking downstream effects of testosterone, which is known to masculinize the developing brain through ...

Selective inhibitors of COX-2-selective NSAIDs are effective antiinflammatory and analgesic drugs with improved upper-GI safety compared ... ischemic stroke, and transient ischemic attacks).