Diffuse normolipemic plane xanthoma is characterized by large, yellow-brown flat, xanthomatous skin lesions usually involving the eyelids, sides of the neck, upper trunk, buttocks, and the ...

Another prominent feature is the presence of cutaneous xanthomas. These consist of soft, yellow papules and nodules, which are commonly located in the extensor aspects of the knees and elbows ...

They may also have cholesterol deposits (xanthomas) visible under the skin or built up in tendons. PCSK9 mutations can either ...