Similarly to mice that lack other regulators of the cytoskeleton, HEM1-deficient T cells showed decreased activation and proliferation compared with wild-type T cells. Surprisingly, some T-cell ...

Our group is highly multidisciplinary, as we use a combination of “OMICs”, state of the art microscopy, molecular and cellular biology, animal models and patient material. Our ultimate goal is to ...

we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions. This work enables us to apply our findings to understand disease processes and identify new ...