While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

Mutations in an organism's DNA are a part ... But, a rigorous system of checks and balances is in place through the DNA repair machinery. The errors that slip through the cracks may sometimes ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

Learn more about how researchers zoomed in on the genomes of Chornobyl's dogs.

Scientists at Children's Medical Research Institute (CMRI) have solved a big mystery in cancer research—why cells die in ...

Genome editing with CRISPR-Cas is often associated with the induction of mutations. However, a team of researchers from the ...

If DNA damage is not properly repaired, mutations can occur, which may result in diseases like cancer. Cells use repair systems to fix this damage, with specialized proteins locating and binding ...

He explores how flaws in the transcription and DNA repair pathways contribute to cancer predisposition, accelerated aging ...

Researchers from NC State and Columbia University analyzed the genomes of dogs in Chornobyl City and the nearby Nuclear Power ...

They also sequenced more than 400 genomes of treated and untreated cells to determine what mutations were caused by the DNA repair pathway inactivation, by the TMZ treatment, and by their combination.

Scientists have analyzed thousands of mutations in the BRCA2 cancer gene, offering crucial insights. This research could help mitigate patient concerns or guide tailored treatments. By utilizing ...