NMR is used in chemistry and related fields for ... aggregates implicated in Huntington’s disease. The single stranded DNA binding protein RPA plays a pivotal role in DNA replication.

The NMR and Drug Metabolism Core works closely with the Baylor Center for Drug Discovery ... A more economical approach that enables the generation of greater small-molecule diversity is the ...

We also use NMR spectroscopic titration techniques. This work reveals a novel DNA interaction involving a dimeric 'winged helix' domain protein that differs from predictions. While the two ...

Currently her main area of interest is on the application of solution NMR techniques to the analysis of interesting biochemical questions. In collaboration with the Jamieson lab, the Suarez lab is ...

Elizabeth Jamieson’s lab examines how various DNA lesions damage DNA. She and her students use differential scanning calorimetry to see how these lesions alter the thermodynamic stability of the DNA ...

Researchers describe a new potential role for oleanic acid as a modulator of the DNA damage response following camptothecin ...

By comparing the NMR spectra of authentic and potentially ... by detecting the unique spectral characteristics of adulterants. DNA-based techniques: Random Amplified Polymorphic DNA (RAPD ...

Oleanolic acid, found in grapes, could increase the effectiveness of chemotherapy, reducing the amount of drug needed.