What is a desmoid tumor? A desmoid tumor is a rare fibrous growth that can start in the arms, legs, or torso (body). They most commonly grow in the abdomen (belly). These tumors start in connective ...

Background Desmoid tumor is a rare type of cancer that develops in the tissues that form tendons and ligaments. These tumors, also called aggressive fibromatosis, are considered benign with no ...

Mark Agulnik, MD, discusses the efficacy and adverse events in the DeFi trial for patients with desmoid tumors given nirogacestat.

The results of the DeFi trial of nirogacestat in 142 adults with progressing desmoid tumours showed a significant 71% improvement with the drug on progression-free survival (PFS) compared to ...