Diabetic patients referred for duplex scanning of the lower extremity arteries were included if they had foot lesions such as ulcers, gangrene, or tissue necrosis and had no palpable pedal pulses.

These issues put patients with diabetes at greater risk for foot ulcers, non-healing wounds, and infections that, left untreated, often result in loss of a limb. Jose Samano faced a dire situation ...

We examined the role of vascular function and inflammation in the development and failure to heal diabetic foot ulcers (DFUs ... to heal had higher tumor necrosis factor-α, monocyte ...

Despite this, the gangrene continued to progress ... two procedures have been combined to save a severely infected diabetic foot from major amputation, as well as reconstruct the foot to allow ...

The proposed study would monitor and evaluate the rates (and recurrent rates) of foot ulceration, infection and gangrene resulting from diabetes, resource use and costs (including referral rates), ...