Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...

The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results ...

Researchers from Stanford University and LMU have uncovered how cells renew their endoplasmic reticulum’s protein factories.

Our research group studies the mechanisms of protein trafficking and quality control at the endoplasmic reticulum (ER) in mammalian cells. A major focus of research is on the COPII protein machinery ...

Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS ...

Researchers at University College Dublin (UCD) have discovered that a mutation in a gene called emc1 causes major vision ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

Our research group is investigating the signalling and biological functions of GDNF neurotrophic family ligands and endoplasmic reticulum located CDNF/MANF protein families, both within and outside of ...

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...