Cells have extensive sets of intracellular membranes, which together compose the endomembrane system. The endomembrane system was first discovered in the late 1800s when scientist Camillo Golgi ...

The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results ...

Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...

Zika virus, infamous for causing microcephaly, manipulates a host protein called ANKLE2 to assist its replication, which also ...

We have identified the IRE1/XBP1 branch of the Unfolded Protein Response (UPR) or endoplasmic reticulum (EnR) stress response as a previously unexplored therapeutic vulnerability in MYC-driven breast ...

Researchers at University College Dublin (UCD) have discovered that a mutation in a gene called emc1 causes major vision ...

PDAT enzymes use membrane phospholipids as direct fatty acid donors to generate triglycerides stored in lipid droplets. This ...

Blood tests have revealed research results that can increase the accuracy of breast cancer diagnosis.A joint research team of professors Kim Seung-il and Kim ...

Our research group is investigating the signalling and biological functions of GDNF neurotrophic family ligands and endoplasmic reticulum located CDNF/MANF protein families, both within and outside of ...

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...