The prevailing model of geometry-based iterative sorting posits that during maturation the early endosome extends tubules that become the ERC, whereas the main body of the early endosome becomes ...

引言多囊泡体（MVBs）是细胞内的重要细胞器，在细胞质量控制中扮演着关键角色。MVB膜通过内陷和切割形成腔内小泡（ILVs），负责分选蛋白质货物，这一过程按当今的理解需要ESCRT蛋白复合体消耗ATP来完成【1】。近些年研究显示，生物分子凝聚体是细胞 ...

This newly decoded process is essential for the survival of plants. The study "Biomolecular condensates mediate bending and scission of endosome membranes" was published in Nature. "Condensates can be ...

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Researchers have found that cellular droplets function in more diverse ways than previously known. The ability to fission ...

CINCINNATI (WKRC) - Healthcare providers are introducing a new combo treatment to help rejuvenate aging skin. This treatment ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

Nanomedicine. 2012;7(8):1253-1271. Although passive targeting approaches form the basis of clinical therapy, they suffer from several limitations. Ubiquitously targeting cells within a tumor is ...

The research team discovered that combining siRNA with ionizable drugs - compounds that change their charge based on pH levels - enhances the stability and delivery efficiency of siRNA inside cells, ...

After assembling all of the puzzle pieces, we realized that structure was an endosome," Newman said. "That discovery ...

Cereb Cortex. 14;30(4):2452-2464 Lu Y, West RJH, Pons M, Sweeney ST, Gao FB. Ik2/TBK1 and Hook/Dynein, an adaptor complex for early endosome transport, are genetic modifiers of FTD-associated mutant ...