Studies on how endothelial 'tip, stalk and phalanx cells' form sprouts have identified promising candidate targets with complementary mechanisms to VEGF. This Review provides a conceptual ...
Atherosclerosis involves multiple processes including endothelial dysfunction ... to other cellular processes such as inflammation, apoptosis and matrix alterations. The contribution of vascular ...
The quality and quantity of the ceramide response, in combination with other signals, determines whether adaptation or apoptosis ensues. This pathway is evolutionarily conserved ... Gemcitabine kills ...
GlobalData’s report assesses the drugs in the Angiopoietin 2 pipeline by therapy areas, indications, stages, MoA, RoA, molecule type and the key players in the development pipeline.
Disturbed blood flow generates frictional forces (shear stress) that trigger pathophysiological changes in endothelial cells that promote atherosclerosis initiation and the progression of plaques into ...
This valuable study on strategies used by Pseudomonas to subvert hots immunity identifies a new immune evasion strategy. The study presents solid evidence on the cleavage of VgrG2B by Caspase 11 and ...
The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...