Chemicals were then used to coax these stem cells into becoming four types of cell found in the earliest stages of the human embryo: epiblast cells, which become the embryo proper (or foetus ...

This work presents a valuable finding on how the interplay between transcription factors SOX2 and OCT4 establishes the pluripotency network in early mouse embryos. Despite the high quality of the data ...

Our laboratory sits at the interface between stem cell biology and developmental neuroscience. We use pluripotent stem cells to model neurological development and disease with a specific focus on ...

In mammals, female (XX) and male (XY) cells exhibit sex chromosome dimorphism. To achieve dosage compensation of X-linked ...

But to maximize their potential, scientists needed to understand how to apply their mouse-cell knowledge to these stem cells. Tesar's breakthrough discovery of an additional type of cell—epiblast stem ...

Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and ...

7.Sugimoto M, Kondo M, Koga Y, Shiura H, Ikeda R, Hirose M, Ogura A, Murakami A, Yoshiki A, Chuva de Sousa Lopes SM, Abe K. "A simple and robust method for establishing homogeneous mouse epiblast stem ...