EurekAlert!5 个月
Increased systemic iron levels induce the expression of hepcidin via TfR/Hfe (IMAGE)
Higher EPO and HIF lead to the secretion of ERFE from erythroid precursor cells, which attenuates the BMP6 signaling cascade via GDF15/TWSG1. In the absence of BMP6, TMPRSS6 binds to ALK2 ...