Gene regulation in multicellular eukaryotes is complex, with many layers of regulation. Two fundamental mechanisms of gene regulation involve transcription factors and microRNAs, a large class of ...

The recent discoveries and models presented in this Review echo the visionary predictions of McClintock and those of a few pioneers on the significance of TEs for eukaryotic gene regulation.

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...

The correct regulation of gene expression is essential for the proper functioning of the cell, and incorrect regulation of genes is central to the mechanisms of many diseases. My interests rest in ...