Deep functional characterization of Fragile X syndrome patient and isogenic neurons using all-optical electrophysiology and machine learning identifies a validated, FMR1-dependent cellular ...

We demonstrate that in response to changes in activity, cultured cortical pyramidal neurons regulate intrinsic excitability to promote stability in firing. Depriving pyramidal neurons of activity ...

Typically when we hear "neuroplasticity," we imagine neural excitability ... when we activate our muscles, mechanical forces are produced. These affect the muscle itself, tendon, bone, and ...