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新型四氧化三铁荧光纳米探针构建及活性研究
基质金属蛋白酶-2 (MMP-2)是一类重要的肿瘤标志物,开发能特异性检测MMP-2的智能型荧光纳米探针,对于癌症的早期诊断与治疗都至关重要 。利用亚铜离子催化的“点击”化学反应将荧光素 (FITC)和多肽底物KCPLGVR偶联,并与dp-PEG-Mal修饰的四氧化三铁纳米颗粒 ...
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