随着全球人口老龄化,衰老相关的科学问题正日益受到关注。然而,衰老是一个复杂的生物学过程,表现为多器官、多组织功能的系统性下降,并与多种慢性疾病密切相关。此前有研究表明,将年轻个体的血液输入老年个体可以在全身范围内改善其功能状态,说明造血系统对于整体衰 ...
【导读】小细胞肺癌(SCLC)患者死亡的主要原因是转移,肝脏是其远处转移的主要部位。尽管具有这样的临床意义,但 SCLC 与肝微环境相互作用促进转移的机制仍不清楚。1月7日,中山大学研究团队在期刊《Journal of Experimental & ...
1 Day HSCS -5.88% DJIA 0.68% Russell 2K -0.38% Health Care/Life Sciences 0.43% ...
Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their ...
Editas Medicine在开发体内基因编辑疗法方面处于领先地位,拥有一个强大的管线,旨在治疗广泛的疾病。该公司从布罗德研究所和哈佛大学获得了CRISPR/Cas12a和CRISPR/Cas9基因组编辑系统用于人类医药的独家许可。
Scientists at La Jolla Institute for Immunology (LJI) have discovered how a mutated gene kicks off a dangerous chain of ...
Srivastava and colleagues said their study validated a new approach to gene therapy in severe hemophilia A -- through transplantation, after myeloablative conditioning, of autologous HSCs ...
Achieved in vivo preclinical proof of concept of editing hematopoietic stem cells in non-human primates as a key step toward developing ...
The deal is set to help Vertex’s development of next-generation gene editing therapies for sickle cell disease and ...