Genital herpes simplex virus (HSV) infections are frequently asymptomatic or undiagnosed, but more than half the US population is seropositive for HSV, and about one-fifth are positive for HSV-2.

All organisms—from fungi to mammals—have the capacity to evolve and adapt to their environments. But viruses are master ...

If the clinical sample contains viable virus, cytopathic effects due to the herpes virus replication occur after several days, signaling the recovery of HSV-1/2 and VZV from the sample.

The global genital herpes treatment market is expected to grow at a CAGR of 5.2% from 2023 to 2033. Market valuation will ...

However, contamination is a recurrent problem of helper-mediated production systems and, despite using replication-defective HSV constructs, purification remains essential. In spite of these ...

Our lab focuses primarily on drug development, specifically on novel small-molecule inhibitors of herpes simplex virus replication. We are investigating their structure-activity relationships, their ...

University of Pittsburgh researchers uncovered a surprising link between Alzheimer's disease and herpes simplex virus-1 (HSV-1), suggesting that viral infections may play a role in the disease. The ...