Several components of the hedgehog (Hh) pathway are crucial to basal cell carcinoma (BCC) tumorigenesis. Primary cilia have emerged as key organelles in Hh signal transduction in mammalian systems ...
“These damages cause the cilia to stop working properly,” explains Mathias De Decker, first author of the study. “We saw that an important signaling pathway – the sonic hedgehog (Shh) signaling ...
John Hood, CEO, Endeavor BioMedicines discusses partnering with advocacy groups to increase awareness of clinical trials for idiopathic pulmonary fibrosis.